专利名称：ANTI-RANKL ANTIBODY
发明人：HONMA, Masashi，本間 雅,SUZUKI, Hiroshi，鈴木 洋史,KARIYA, Yoshiaki，苅谷 嘉buchi
顕,HAYASHI, Madoka，林 円香,IKEBUCHI,
Yuki，池淵 祐樹
申请号：JP2015/054806
申请日：20150220
公开号：WO2015/125922A1
公开日：
20150827
专利内容由知识产权出版社提供
摘要：The purpose of the present invention is to provide a new therapeutic agent for bone metabolism-related disease. Provided is an anti-RANKL antibody, or a functional fragment thereof, that binds with the RANKL extracellular domain, displays osteoblast-activating capability by crosslinking two or more RANKL trimers, and at the same time, displays mature osteoclast formation-inhibiting capability by inhibiting the binding of RANKL to RANK.
申请人：THE UNIVERSITY OF TOKYO，国立大学法人東京大学
地址：〒1138654 JP,〒1138654 JP
国籍：JP,JP
代理人：THE PATENT CORPORATE BODY ARUGA PATENT OFFICE，特許業務法人アルガ特許事務所
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